| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0486 | FALEC | ECM1 | RNA-RNA | co-expression | Depletion of ncRNA-a1 (activating long ncRNA 1, LINC00568), results in decreased ECM1 levels, suggesting a direct activating function of ncRNA-a1 on its neighboring gene. | 21502407 | LncRNADisease | ||
| EL0486 | FALEC | BMI1 | RNA-DNA | regulation | FAL1 associates with the epigenetic repressor BMI1 and regulates its stability in order to modulate the transcription of a number of genes including CDKN1A. | 25203321 | |||
| EL0486 | FALEC | p21 | RNA-DNA | regulation | The oncogenic activity of FAL1 is partially attributable to its repression of p21. | 25203321 | |||
| EL0486 | FALEC | BMI1 | RNA-Protein | regulation | The oncogenic activity of FAL1 was mediated in part by its interaction with BMI1, a component of the chromatin-modifying Polycomb repressive complex 1, which resulted in increased stabilization of BMI1 protein and transcriptional repression of genes involved in processes such as cell proliferation and apoptosis. | 25367941 | |||