| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0350 | Dlx6os1 | DLX5 | RNA-DNA | regulation | DLX6-AS1 specifically cooperates with Dlx-2 to increase the transcriptional activity of the Dlx-5/6 enhancer in a target and homeodomain-specific manner. | 16705037 | LncRNADisease | ||
| EL0350 | Dlx6os1 | DLX6 | RNA-DNA | regulation | DLX6-AS1 specifically cooperates with Dlx-2 to increase the transcriptional activity of the Dlx-5/6 enhancer in a target and homeodomain-specific manner. | 16705037 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx6 | RNA-DNA | regulation | Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. | 18184812 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx2 | RNA-Protein | binding | Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. | 18184812 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx6 | RNA-DNA | regulation | Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. Consistent with this function, Evf exhibits a coincident expression profile with Dlx2. | 18184812 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx2 | RNA-Protein | binding | Evf2 interacts in trans with the homeobox transcription factor Dlx2 to regulate the expression of the Dlx6 gene that it encompasses. Consistent with this function, Evf exhibits a coincident expression profile with Dlx2. | 18184812 | LncRNADisease | ||
| EL0350 | Dlx6os1 | DLX2 | DNA-TF | regulation | Evf2 regulates the binding of the DLX2 transcription factor to its originating enhancer element, which in turn regulates the transcriptional activity of the enhancer. | 18562676 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx2 | RNA-Protein | binding | Single-stranded Evf2 forms a complex with the product of a third homeodomain gene Dlx2 whose sequence lies elsewhere in the mouse genome. | 19239885 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx2 | RNA-Protein | binding | The 3.8-kb Evf-2 ncRNA, which is transcribed from an ultraconserved region, forms a complex with the homeodomain-containing protein Dlx2. | 19571179 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx6 | RNA-DNA | regulation | Evf-2 was previously shown to regulate binding of the Dlx2 transcription factor to the ultraconserved enhancer to activate the expression of the encompassed Dlx6 gene during neurogenesis. | 20137068 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx2 | RNA-Protein | binding | Evf-2 was previously shown to regulate binding of the Dlx2 transcription factor to the ultraconserved enhancer to activate the expression of the encompassed Dlx6 gene during neurogenesis. | 20137068 | LncRNADisease | ||
| EL0350 | Dlx6os1 | DLX | DNA-TF | regulation | the lincRNA Evf2 is transcribed from an ultraconserved distal enhancer that recruits positive (i.e., DLX) and negative (i.e., MECP2) transcription factors to the enhancer to modulate the expression of adjacent protein-coding genes | 20380817 | LncRNADisease | ||
| EL0350 | Dlx6os1 | MECP2 | DNA-TF | regulation | the lincRNA Evf2 is transcribed from an ultraconserved distal enhancer that recruits positive (i.e., DLX) and negative (i.e., MECP2) transcription factors to the enhancer to modulate the expression of adjacent protein-coding genes | 20380817 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-5 | RNA-DNA | regulation | Evf2 forms a complex with Dlx-2 and recruits Dlx-2 to induce the enhancer activities of ei and eii, resulting in induced expression of both Dlx-5 and -6. | 20573714 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-6 | RNA-DNA | regulation | Evf2 forms a complex with Dlx-2 and recruits Dlx-2 to induce the enhancer activities of ei and eii, resulting in induced expression of both Dlx-5 and -6. | 20573714 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-2 | RNA-Protein | binding | Evf2 forms a complex with Dlx-2 and recruits Dlx-2 to induce the enhancer activities of ei and eii, resulting in induced expression of both Dlx-5 and -6. | 20573714 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-5 | RNA-Protein | regulation | The lncRNA Evf-2 is a putative direct positive regulator of the transcription factor Dlx-2, and is consequently an indirect positive regulator of Dlx-5 and Dlx-6. | 20951849 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-6 | RNA-Protein | regulation | The lncRNA Evf-2 is a putative direct positive regulator of the transcription factor Dlx-2, and is consequently an indirect positive regulator of Dlx-5 and Dlx-6. | 20951849 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-2 | RNA-Protein | regulation | The lncRNA Evf-2 is a putative direct positive regulator of the transcription factor Dlx-2. | 20951849 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-5/6 enhancer | RNA-DNA | regulation | Cooperates with Dlx-2 in vivo to increase the transcriptional activity of the Dlx-5/6 enhancer. | 21256239 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx-5/6 enhancer | RNA-DNA | regulation | Cooperates with Dlx-2 in vivo to increase the transcriptional activity of the Dlx-5/6 enhancer. | 21256239 | LncRNADisease | ||
| EL0350 | Dlx6os1 | Dlx6 | RNA-DNA | regulation | Evf-2 modulates transcription of Dlx6 by recruiting DLX2 and MECP2 to the ultraconserved ei enhancer element that is also transcribed as part of Evf-2 itself. | 21936910 | LncRNADisease | ||
| EL0350 | Dlx6os1 | DLX2 | RNA-Protein | binding | Evf-2 modulates transcription of Dlx6 by recruiting DLX2 and MECP2 to the ultraconserved ei enhancer element that is also transcribed as part of Evf-2 itself. | 21936910 | LncRNADisease | ||
| EL0350 | Dlx6os1 | MECP2 | RNA-Protein | binding | Evf-2 modulates transcription of Dlx6 by recruiting DLX2 and MECP2 to the ultraconserved ei enhancer element that is also transcribed as part of Evf-2 itself. | 21936910 | LncRNADisease | ||