Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0462 ENST00000460164 triple-negative breast cancer microarray, qPCR etc. triple-negative breast cancer tissue up-regulated expression We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. 25996380 Lnc2Cancer
EL0467 LINC01096 triple-negative breast cancer microarray, qPCR etc. TNBC tissue down-regulated expression The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. 26078338 Lnc2Cancer
EL0578 HOTAIR triple-negative breast cancer microarray, qPCR etc. triple-negative breast cancer tissue up-regulated expression We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. 25996380 Lnc2Cancer
EL0578 HOTAIR triple-negative breast cancer N/A Triple-negative breast cancer (TNBC) samples up-regulated expression HOTAIR has been known to induce tumor growth and metastasis in breast cancer. Depleting HOTAIR alone phenocopies the dual treatment in growth suppression. We show that expression of HOTAIR is regulated by β-catenin through a LEF1/TCF4-binding site. 25883211
EL0747 LINC-ROR triple-negative breast cancer microarray, qPCR, Western blot etc. breast cancer tissue, cell lines (HEK293T, MCF-7, HS578T, MDA-MB-231) up-regulated N/A LincRNA-RoR is upregulated in TNBC and in metastatic disease and knockdown restores miR-145 expression.The lincRNA-RoR/miR-145/ARF6 pathway is critical to TNBC metastasis and could serve as biomarkers or therapeutic targets for improving survival. 25253741 LncRNADisease Lnc2Cancer
EL0750 LINK-A triple-negative breast cancer N/A N/A N/A interaction Both LINK-A expression and LINK-A-dependent signalling pathway activation correlate with triple-negative breast cancer (TNBC), promoting breast cancer glycolysis reprogramming and tumorigenesis. 26751287
EL0853 MALAT1 triple-negative breast cancer microarray, qPCR etc. triple-negative breast cancer tissue up-regulated expression We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. 25996380 Lnc2Cancer
EL0853 MALAT1 triple-negative breast cancer tissue microarray; immunoblotting, polymerase chain reaction, loss and gain of gene MDA-MB-231 cells up-regulated N/A N/A 26917489
EL0979 NONHSAT012762 triple-negative breast cancer microarray, qPCR etc. TNBC tissue up-regulated expression The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. 26078338 Lnc2Cancer
EL0983 NONHSAT125629 triple-negative breast cancer microarray, qPCR etc. TNBC tissue down-regulated expression The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. 26078338 Lnc2Cancer
EL1056 PCAT6 triple-negative breast cancer microarray, qPCR etc. triple-negative breast cancer tissue up-regulated expression We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. 25996380 Lnc2Cancer
EL1311 TCONS_l2_00003938 triple-negative breast cancer microarray, qPCR etc. triple-negative breast cancer tissue up-regulated expression We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC. 25996380 Lnc2Cancer
EL1511 XR_250621.1 triple-negative breast cancer microarray, qPCR etc. TNBC tissue up-regulated expression The results demonstrated that lncRNAs NONHSAT125629 and ENST00000503938 were upregulated and that XR_250621.1 and NONHSAT012762 were down-regulated in the tumor samples compared with NT samples. These qPCR results are consistent with the microarray data. 26078338 Lnc2Cancer