Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0582 HOTTIP tongue squamous cell carcinoma qPCR etc. tongue cancer tissue up-regulated expression In our study, results indicated that lncRNA HOTTIP was highly expressed in TSCC compared with adjacent non-malignant tissues and positively correlated with T stage, clinical stage, and distant metastasis in TSCC patients. 26058875 Lnc2Cancer
EL0698 LINC01468 tongue squamous cell carcinoma microarray, qPCR etc. tongue SCC tissue up-regulated regulation Overexpression of lnc-SPRR2D-1 and lnc-PPP2R4-5 was found in the tongue SCC tissue. Overexpression of the lnc-MBL2-4:3 in the tongue SCC was highly significant in comparison with the paired normal epithelia. Lnc-AL355149.1-1 was the only lncRNA found to be downregulated in the tongue SCC tissues.The association of lncRNA with the T-stage and nodal status of tongue SCC patients suggested that lncRNA deregulation was involved in the pathogenesis of tongue SCC. 25045670 Lnc2Cancer
EL0699 LINC01503 tongue squamous cell carcinoma microarray, qPCR etc. tongue SCC tissue up-regulated regulation Overexpression of lnc-SPRR2D-1 and lnc-PPP2R4-5 was found in the tongue SCC tissue. Overexpression of the lnc-MBL2-4:3 in the tongue SCC was highly significant in comparison with the paired normal epithelia. Lnc-AL355149.1-1 was the only lncRNA found to be downregulated in the tongue SCC tissues.The association of lncRNA with the T-stage and nodal status of tongue SCC patients suggested that lncRNA deregulation was involved in the pathogenesis of tongue SCC. 25045670 Lnc2Cancer
EL0702 LINC01527 tongue squamous cell carcinoma microarray, qPCR etc. tongue SCC tissue up-regulated regulation Overexpression of lnc-SPRR2D-1 and lnc-PPP2R4-5 was found in the tongue SCC tissue. Overexpression of the lnc-MBL2-4:3 in the tongue SCC was highly significant in comparison with the paired normal epithelia. Lnc-AL355149.1-1 was the only lncRNA found to be downregulated in the tongue SCC tissues.The association of lncRNA with the T-stage and nodal status of tongue SCC patients suggested that lncRNA deregulation was involved in the pathogenesis of tongue SCC. 25045670 Lnc2Cancer
EL0762 lnc-AL355149.1-1 tongue squamous cell carcinoma microarray, qPCR etc. tongue SCC tissue down-regulated regulation Overexpression of lnc-SPRR2D-1 and lnc-PPP2R4-5 was found in the tongue SCC tissue. Overexpression of the lnc-MBL2-4:3 in the tongue SCC was highly significant in comparison with the paired normal epithelia. Lnc-AL355149.1-1 was the only lncRNA found to be downregulated in the tongue SCC tissues.The association of lncRNA with the T-stage and nodal status of tongue SCC patients suggested that lncRNA deregulation was involved in the pathogenesis of tongue SCC. 25045670 Lnc2Cancer
EL0861 MEG3 tongue squamous cell carcinoma microarray, MSP, Western blot, knockdown etc. TSCC tissue, cell lines (SCC-15, CAL27 etc.) down-regulated N/A We report here that miR-26a and lncRNA MEG3 gene expression were both strongly reduced in TSCC compared with levels in matched nonmalignant tissues, and combined low expression levels of both miR-26a and MEG3 emerged as an independent prognostic factor for poor clinical outcome in TSCC patients. 24343426 Lnc2Cancer
EL1431 UCA1 tongue squamous cell carcinoma N/A N/A N/A expression Meaningfully, the expression levels of UCA1 lncRNA were dramatically higher in TSCC tissues than those in paired ANTs.? 24817925 LncRNADisease
EL1431 UCA1 tongue squamous cell carcinoma qPCR etc. TSCC tissue up-regulated N/A The expression levels of lncRNA UCA1 were significantly elevated in TSCC tissues (P < .0001) and were statistically correlated with lymph node metastasis (P = .0371). Over-expression of UCA1 lncRNA could promote metastatic but not proliferation ability of TSCC cells. 24332332 Lnc2Cancer