Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0215 ATXN7L3B spinocerebellar ataxia type 7 N/A N/A N/A N/A STAGA is required for the transcription initiation of miR-124, which in turn mediates the post-transcriptional cross-talk between lnc-SCA7, a conserved long noncoding RNA,and ATXN7 mRNA. In SCA7, mutations in ATXN7 disrupt these regulatory interactions and result in a neuron-specific increase in ATXN7 expression. Strikingly, in mice this increase is most prominent in the SCA7 disease-relevant tissues, namely the retina and cerebellum. 25306109 LncRNADisease
EL1171 RRP1B Spinocerebellar ataxia type 7 N/A N/A N/A expression CTCF is required for SCAANT1 expression. Loss of SCAANT1 derepressed ataxin-7 sense transcription in a cis-dependent fashion and was accompanied by chromatin remodeling. 21689595 LncRNADisease
EL1171 RRP1B Spinocerebellar ataxia type 7 N/A N/A N/A mutation For example, SCA7/ATXN7 antisense RNA 1 (SCAANT1) is an lncRNA transcribed antisense to the gene mutated in spinocerebellar ataxia type 7 (ATXN7), and it functions as a repressor of ATXN7 transcription 22814587 LncRNADisease
EL1171 RRP1B Spinocerebellar ataxia type 7 N/A N/A N/A regulation Genomic context links lncRNAs to disease genes/loci and related pathways 23791884 LncRNADisease
EL1171 RRP1B Spinocerebellar ataxia type 7 N/A N/A N/A expression Long ncRNA SCAANT1 is implicated in a type of polyglutamine disorder, spinocerebellar ataxia type 7 (SCA7). 24624135 LncRNADisease