| Related LncRNAs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source |
| EL0059 | AK130977 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL0217 | AX746718 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL0334 | DDR2 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL0526 | GAS5 | malignant pleural mesothelioma | qPCR, knockdown etc. | MPM tissue, cell lines (SPC111, SPC212, ZL34, ZL55) | down-regulated | N/A | GAS5 expression was lower in MPM cell lines compared to normal mesothelial cells. GAS5 was upregulated upon growth arrest induced by inhibition of Hedgehog and PI3K/mTOR signalling in in vitro MPM models. The increase in GAS5 lncRNA was accompanied by increased promoter activity. Silencing of GAS5 increased the expression of glucocorticoid responsive genes glucocorticoid inducible leucine-zipper and serum/glucocorticoid-regulated kinase-1 and shortened the length of the cell cycle. Drug induced growth arrest was associated with GAS5 accumulation in the nuclei. GAS5 was abundant in tumoral quiescent cells and it was correlated to podoplanin expression. | 24885398 | Lnc2Cancer |
| EL0813 | LOC100131831 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL0973 | NEAT1 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL1050 | PAX8-AS1 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL1076 | POT1-AS1 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL1102 | PVT1 | malignant pleural mesothelioma | microarray, qPCR, knockdown etc. | MPM tissue, MPM cell lines | up-regulated | N/A | Our results suggest that C-MYC and PVT1 CNG promotes a malignant phenotype of MPM, with C-MYC CNG stimulating cell proliferation and PVT1 both stimulating proliferation and inhibiting apoptosis. | 24926545 | Lnc2Cancer |
| EL1233 | SNHG8 | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |
| EL1234 | SNORA17B | malignant pleural mesothelioma | microarray, qPCR etc. | MPM tissue, cell lines (H28, H226, H2052, H2452, MSTO etc.) | up-regulated | N/A | AK130977 and AX746718 were both found to be down-regulated via both microarray and RT-qPCR (AK130977 Microarray (MA) = -5.207, RT-qPCR = -1.6; AX746718 MA = -3.37, RT-qPCR = -4.6), with AK130977 demonstrating fairly small changes using RT-qPCR. Similarly, BX648695, AK129685, EF177379, AK054908, AK130275, AF268386 and NR_003584 all demonstrated consistent up-regulation using both microarrays and RT-qPCR. | 23976967 | Lnc2Cancer |