| Related LncRNAs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source |
| EL0237 | BCYRN1 | esophageal cancer | ISH, Northern hybridization etc. | esophageal cancer tissue | up-regulated | expression | BC200 RNA was expressed in carcinomas of the breast, cervix, oesophagus, lung, ovary, parotid, and tongue, but not in corresponding normal tissues. | 9422992 | LncRNADisease Lnc2Cancer |
| EL0556 | H19 | esophageal cancer | qPCR, Western blot, knockdown etc. | esophageal cancer tissue, cell lines (TE-1, TE-10, Eca-1, Eca-109, KYSE1170) | up-regulated | expression | The expression of H19 was significantly increased and associated with tumor depth and metastasis in 133 EC samples. In addition, it was identified that an upregulation of H19 induced epithelial-to-mesenchymal transition. In conclusion, H19 has a significant role in the development of EC and may serve as a potential prognostic marker and therapeutic target for EC. | 26171017 | Lnc2Cancer |
| EL1063 | PEG10 | esophageal cancer | qPCR, Western blot etc. | esophageal cancer tissue, cell lines (EC9706, KYSE150) | up-regulated | expression | LncRNA PEG10 was expressed at higher levels in esophageal cancer tissues than in adjacent non-neoplastic tissues (P<0.05). This relatively high expression was significantly associated with the occurrence of lymph node metastases (P<0.05). Apoptosis and migration rates were significantly decreased in two esophageal cancer cell lines (EC9706 and KYSE150) transfetced with si-LncRNA PEG10 (P<0.05). | 25591808 | Lnc2Cancer |