Related LncRNAs
ID	lncRNA Name	Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
EL0332	DBET	Facioscapulohumeral muscular dystrophy	Gene expression study in human cells to build pathways involved by DBE-T in FSHD patients	N/A	N/A	N/A	DBE-T, a chromatin-associated noncoding RNA produced selectively in FSHD patients that coordinates de-repression of 4q35 genes. DBE-T recruits the Trithorax group protein Ash1L to the FSHD locus, driving histone H3 lysine 36 dimethylation, chromatin remodeling, and 4q35 gene transcription.	22541069
EL0332	DBET	Facioscapulohumeral muscular dystrophy	N/A	N/A	N/A	mutation	The activatory long non-coding RNA DBE-T reveals the epigenetic etiology of facioscapulohumeral muscular dystrophy.	22710800	LncRNADisease
EL0332	DBET	Facioscapulohumeral muscular dystrophy	N/A	N/A	N/A	regulation	Epigenetic deregulation of lncRNAs genes is associated with disease	23791884	LncRNADisease
EL0332	DBET	Facioscapulohumeral muscular dystrophy	N/A	N/A	N/A	regulation	In contrast, in FSHD patients, a deletion of D4Z4 repeats results in cis production of the DBE-T lncRNA that binds to protein complexes, reorganizes the chromatin state of the FSHD locus, and reactivates the repressed 4q35 genes.	24667321	LncRNADisease
EL0332	DBET	Facioscapulohumeral muscular dystrophy	N/A	N/A	N/A	expression	As a result, this region becomes more prone to transcription and gives rise to the activatory lncRNA DBE-T. DBE-T is mainly produced in FSHD patients and mediates the aberrant activation of the FSHD locus.	24685002	LncRNADisease