Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0564 HCP5 AIDS N/A N/A N/A mutation HCP5 genotyping could serve as a simple screening tool for ABC-HSR. 18684101 LncRNADisease
EL0564 HCP5 AIDS N/A N/A N/A mutation A polymorphism (rs2395029, G824T) in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro. 19935381 LncRNADisease
EL0564 HCP5 AIDS N/A N/A N/A expression A total of 245 HIV patients were included in the study. A good correlation between HLA-B*5701 and HCP5 was observed (negative and positive predictive values of 100% and 93%, respectively). 20534626 LncRNADisease
EL0573 HLA-AS1 AIDS N/A N/A N/A mutation HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles. 18982067 LncRNADisease
EL0973 NEAT1 AIDS N/A N/A N/A expression We found NEAT-1 to be one of several lncRNAs whose expression is changed by HIV-1 infection, and we have characterized its role in HIV-1 replication. 23362321 LncRNADisease
EL1013 NRON AIDS N/A N/A N/A N/A The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins. Its expression was significantly altered following HIV-1 infection. Its levels were reduced by the early viral accessory protein Nef and increased by the late protein Vpu. 25728138 LncRNADisease
EL1120 RN7SK AIDS N/A N/A N/A Interaction HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP. 20471949 LncRNADisease
EL1120 RN7SK AIDS N/A N/A N/A Interaction Tat efficiently replaces HEXIM1 on the 7SK snRNA in vivo and therefore, it promotes the disassembly of the 7SK/HEXIM/P-TEFb negative transcriptional regulatory snRNP to augment the nuclear level of active P-TEFb. The human 7SK snRNA carries a TAR RNA-like Tat-binding element that is essential for the normal transcriptional regulatory function of 7SK questions the viability of HIV therapeutic approaches based on small drugs blocking the Tat-binding site of HIV TAR. 20976203 LncRNADisease
EL1120 RN7SK AIDS N/A N/A N/A Interaction The 7SK-HMGA1 interaction not only adds an essential facet to the comprehension of transcriptional plasticity at the coupling of initiation and elongation, but also might provide a molecular link between HIV reprogramming of cellular gene expression-associated oncogenesis. 21087998 LncRNADisease
EL1120 RN7SK AIDS N/A N/A N/A expression Stable expression of cdNIPP1 increased CDK9 phosphorylation on Thr(186) and the association of CDK9 with 7SK RNA. The stable expression of cdNIPP1 disrupted the interaction of Tat and PP1 and inhibited HIV-1 transcription. Expression of cdNIPP1 as a part of the HIV-1 genome inhibited HIV-1 replication. 21098020 LncRNADisease
EL1120 RN7SK AIDS N/A N/A N/A Interaction The HIV-1 Tat protein also releases P-TEFb from the 7SK/HEXIM complex during viral infection to promote viral transcription and replication. 22377309 LncRNADisease
EL1121 RN7SL1 AIDS N/A N/A N/A Interaction 7SL RNA, but not the 54-kd signal recognition particle protein, is an abundant component of both infectious HIV-1 and minimal virus-like particles. 16489186 LncRNADisease
EL1121 RN7SL1 AIDS N/A N/A N/A N/A 7SL RNA binding is a conserved feature of human anti-HIV-1 cytidine deaminases. 20926562 LncRNADisease