LncRNA Information
ID EL0466 Name AW112010 Aliases N/A
Species Mus musculus Chromosome 19 Start site 11047612
End site 11050566 Chain minus Exon NO. 3
Assembly GRCm38.p6 Class lncRNA NCBI accession NR_102366
Ensembl ENSMUSG00000075010 Sequence NR_102366 Peptide-related yes
CircRNA N/A Exosomal N/A Structure N/A




Disease
Disease Drug/chemo/stress Method Sample Expression pattern Dysfunction type Description PMID
mucosal immunity Immunoblotting, Immunoprecipitation, Knockdown, overexpresion, RNA-seq, Rescue Experiments, qRT-PCR BMDMs cell, RiboTag (B6N.129 strain) and LysM-Cre (B6.129P2 strain) mice up-regulated expression We show that the translation of a new ORF hidden within the long non-coding RNA Aw112010 is essential for the orchestration of mucosal immunity during both bacterial infection and colitis. 30542152
age-related hearing loss resveratrol and STR1720 knockdown,overexpression,RNA-seq,qRT-PCR,western blot,immunocytochemistry early-onset AHL mouse model, HEI-OC1 cells and the mouse cochlea. up-regulated expression The Arid5b/AW112010 signaling was induced in the aged mouse cochlea and positively modulated the mitochondrial biogenesis to maintain mitochondrial function. 31781342