|
RNA-Seq, Rescue and overexpression, knockdown, In situ hybridization |
N/A |
N/A |
expression |
Toddler is annotated as a non-coding RNA in zebrafish (ENSDARG00000094729), mouse [Gm10664; also called Ende], and human (LOC100506013) and is present in two lncRNA catalogs; however, it contains a 58–amino acid ORF with a predicted signal sequence and high conservation in vertebrates, including human. Local and ubiquitous production of Toddler promote cell movement, suggesting that Toddler is neither an attractant nor a repellent but acts globally as a motogen. |
24407481 |