LncRNA Information | |||||
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ID | EL0034 | Name | A1BG-AS1 | Aliases | A1BG-AS, A1BGAS, NCRNA00181 |
Species | Homo sapiens | Chromosome | 19 | Start site | 58351970 |
End site | 58355183 | Chain | plus | Exon NO. | 4 |
Assembly | GRCh38.p13 | Class | lncRNA | NCBI accession | NR_015380 |
Ensembl | ENSG00000268895 | Sequence | NR_015380 | Peptide-related | N/A |
CircRNA | N/A | Exosomal | N/A | Structure | N/A |
Disease | |||||||||
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Disease | Drug/chemo/stress | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | ||
hepatocellular carcinoma | knockdown | HCCLM3 cells | down-regulated | interaction | LncRNA A1BG-AS1 suppresses proliferation and invasion of hepatocellular carcinoma cells by targeting miR-216a-5p. | 30556161 |
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Methods | Description | PMID | ||||
miR-216a-5p | RNA-RNA | binding | N/A | Mechanistically, A1BG-AS1 functioned as a competing endogenous RNA by directly sponging miR-216a-5p in HCC cells. A1BG-AS1 positively regulated the levels of phosphatase and tensin homolog and SMAD family member 7, which were reduced by miR-216a-5p in HCC cells. | 30556161 | ||||
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