LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL1432 | Name | UCA1 | Aliases | N/A | |
Species | Rattus norvegicus | Chromosome | N/A | Start site | N/A | |
End site | N/A | Chain | N/A | Exon NO. | N/A | |
Assembly | N/A | Class | lincRNA | NCBI accession | N/A | |
Ensembl | N/A | Sequence | N/A |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
focal cardiac ischemia reperfusion injury | microarray, qPCR | primary cardiomyocytes after focal cardiac ischemia reperfusion injury (CIR) | down-regulated | expression | Reduction of UCA1 levels plays a pro-apoptotic role in primary cardiomyocytes partially through stimulation of p27 protein expression. These results are in agreement with the observed levels of UCA1, p27 and apoptosis after cardiac I/R injury, suggesting that UCA1 might have an important role during I/R injury | 25871510 | |||