LncRNA Information
ID EL1420 Name LINC01589 Aliases uc003bgl.1; TCONS_00029353
Species Homo sapiens Chromosome 22 Start site 45604432
End site 45605621 Chain minus Exon NO. 2
Assembly Ensembl Release 89 Class antisense NCBI accession NR_131244
Ensembl ENSG00000238120 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
non-small cell lung cancer microarray, qPCR, Western bolt, knockdown etc. cell lines (A549, CDDP etc.) up-regulated N/A For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP (all P <0.05). Cisplatin resistance in non-small-cell lung cancer cells may relate to the changes in noncoding RNAs. Among these, AK126698 appears to confer cisplatin resistance by targeting the Wnt pathway. 23741487 Lnc2Cancer