LncRNA Information | ||||||
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ID | EL1363 | Name | TRERNA1 | Aliases | LINC00651; treRNA | |
Species | Homo sapiens | Chromosome | 20 | Start site | 50040716 | |
End site | 50041504 | Chain | minus | Exon NO. | 2 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_051976 | |
Ensembl | ENSG00000231265 | Sequence |
Disease | |||||||||
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Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
hepatocellular carcinoma | N/A | hepatoma cells | N/A | expression | miR-190a can silence treRNA post-transcriptionally. Suppression of treRNA by miR-190a led to significant changes of mesenchymal-epithelial transition markers and impaired migration and invasion capability of hepatoma cells. | 26608035 | |||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
Snai1 | RNA-RNA | regulation | KLHL12, ROCK2, TAL1, CMPK1, Snai2, and Snai1 are regulated by ncRNA-a2 through ncRNA-a7, respectively. Knockdown of ncRNA-a7 in A549 cells represses the expression of Snai1 specifically and diminishes cell migration to levels similar to that seen when knocking down Snai1. NcRNA-a7 serves as a transcriptional enhancer of Snai1. | 21502407 | LncRNADisease | ||||
miR-190a | RNA-RNA | regulation | miR-190a can silence treRNA post-transcriptionally. Suppression of treRNA by miR-190a led to significant changes of mesenchymal-epithelial transition markers and impaired migration and invasion capability of hepatoma cells. | 26608035 | |||||