LncRNA Information
ID EL1321 Name TDRG1 Aliases LINC00532
Species Homo sapiens Chromosome 6 Start site 40334954
End site 40379887 Chain plus Exon NO. 2
Assembly Ensembl Release 89 Class antisense NCBI accession NR_024015
Ensembl ENSG00000204091 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
testicular cancer N/A N/A N/A expression The significantly reduced expression of the TDRG1 in patients with seminoma or teratoma indicates that TDRG1 may be a candidate cancer suppressor gene. 21243750 LncRNADisease
aplastic anemia Reverse transcription‑quantitative polymerase chain, small interfering RNA patients exhibiting AA up-regulated interaction The decreased proliferation capability of BMSCs that were treated with Ad‑FGF1 and TDRG1‑small interfering RNA validated the vital effect of TDRG1 on the FGF1 regulatory process of BMSC differentiation. 26460236
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
FGF1 DNA-Protein regulation The increase of acetyl‑histones, H3 and H4 was diminished in the TDRG1 promoter of BMSCs that were infected with Ad‑FGF1, which indicated that the process of acetylation was promoted when the BMSCs were infected with Ad-FGF1. FGF1 induces the proliferation of BMSCs in patients with AA via promoting acetylation in lncRNA of the TDRG1 gene promoter. 26460236