LncRNA Information
ID EL1226 Name SNHG16 Aliases ncRAN
Species Homo sapiens Chromosome 17 Start site 76557766
End site 76565348 Chain plus Exon NO. 4
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_038108, NR_038109, NR_038110, NR_038111
Ensembl ENSG00000163597 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
neuroblastoma N/A N/A N/A regulation It is now becoming increasingly evident that N-myc also regulates the expression of long noncoding RNAs such as T-UCRs and ncRAN. 22936790 LncRNADisease
bladder cancer N/A N/A N/A regulation putative diagnostic, prognostic, and predictive marker 24373479 LncRNADisease
bladder cancer qPCR etc. bladder cancer tissue, cell lines (RT4, T24, J82 etc.) up-regulated N/A Expression of ncRAN was significantly higher in bladder cancers compared with normal tissues and in invasive tumor compared with superficial ones (P < .01). Consistently, ncRAN expressed significantly higher in invasive bladder tumor cell lines (5637, T24, J82) than that in superficial tumor cell line (RT4). Overexpression of ncRAN in RT4 cells significantly enhanced cell proliferation, migration, and invasion. Silencing of ncRAN improved chemotherapy sensitivity in 5637 cells. 21147498 Lnc2Cancer
colorectal cancer qPCR, knockdown etc. CRC tissue, cell lines (LoVo, Caco-2, DLD1, SW620, SW480, HCT8, HCT116 etc.) down-regulated expression Down-regulation of ncRAN, a long non-coding RNA, contributes to colorectal cancer cell migration and invasion and predicts poor overall survival for colorectal cancer patients. 24519959 LncRNADisease Lnc2Cancer