| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1221 | Name | SNHG1 | Aliases | LINC00057; NCRNA00057; U22HG; UHG | |
| Species | Homo sapiens | Chromosome | 11 | Start site | 62851988 | |
| End site | 62855914 | Chain | minus | Exon NO. | 11 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_003098 | |
| Ensembl | ENSG00000255717 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| non-small cell lung cancer | qPCR, knockdown etc. | cell lines (NL9980, L9981, A549, H1299, H460, SK-MES-1 etc.) | up-regulated | expression | Noncoding RNA SNHG1 expression was significantly upregulated in lung cancer cells when compared with normal bronchial epithelial cells. In addition, in vitro assays our results indicated that knockdown of SNHG1 inhibited cell proliferation. | 25818744 | Lnc2Cancer | ||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| N/A | N/A | N/A | expression | The spliced uhg rna, although it is associated with polysomes, has little potential for protein coding, is short-lived, and is poorly conserved between human and mouse. | 8559254 | ||||
| N/A | HeLa cells | N/A | expression | Comparison of the human and mouse u17hg genes has revealed that snorna-encoding intron sequences but not exon sequences are conserved between the two species and that neither human nor mouse spliced u17hg poly(a)+ rnas have the potential to code for proteins. | 9671460 | ||||