LncRNA Information
ID	EL1219	Name	SNCG	Aliases	BCSG1; SR
Species	Homo sapiens	Chromosome	10	Start site	86958618
End site	86963260	Chain	plus	Exon NO.	5
Assembly	Ensembl Release 89	Class	processed transcript	NCBI accession	N/A
Ensembl	ENSG00000173267	Sequence	N/A

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
gastric cancer	microarray, qPCR, in vitro knockdown etc.	gastric cancer tissue, cell lines (SGC7901, MKN45, MKN28)	up-regulated	regulation	AK058003 is frequently upregulated in GC samples and promotes GC migration and invasion in vivo and in vitro. Next, we identified γ-synuclein. (SNCG), which is a metastasis-related gene regulated by AK058003. In addition, we found that the expression of SNCG is positively correlated with that of AK058003 in the clinical GC samples used in our study. Furthermore, we found that the SNCG gene CpG island methylation was significantly increased in GC cells depleted of AK058003. Intriguingly, SNCG expression is also increased by hypoxia, and SNCG upregulation by AK058003 mediates hypoxia-induced GC cell metastasis.	25499222	Lnc2Cancer

Interaction
Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
SNCG	RNA-DNA	regulation	the SNCG gene CpG island methylation was significantly increased in GC cells depleted of AK058003. Intriguingly, SNCG expression is also increased by hypoxia, and SNCG upregulation by AK058003 mediates hypoxia-induced GC cell metastasis.	25499222