LncRNA Information | ||||||
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ID | EL1178 | Name | SARCC | Aliases | N/A | |
Species | Homo sapiens | Chromosome | N/A | Start site | N/A | |
End site | N/A | Chain | N/A | Exon NO. | N/A | |
Assembly | N/A | Class | N/A | NCBI accession | N/A | |
Ensembl | N/A | Sequence | N/A |
Disease | |||||||||
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Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
renal cell carcinoma | a von Hippel-Lindau (VHL)-dependent manner both in RCC cell culture | RCC cell culture and clinical specimens | N/A | N/A | LncRNA-SARCC can post-transcriptionally regulate androgen receptor (AR) | 26973243 | |||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
HIF-2α | DNA-Protein | binding | HIF-2α can transcriptionally regulate the LncRNA-SARCC expression via binding to hypoxia-responsive elements on the promoter of LncRNA-SARCC. | 26973243 | |||||
AR | RNA-Protein | binding | LncRNA-SARCC can post-transcriptionally regulate androgen receptor (AR) by physically binding and destablizing AR protein to suppress AR/HIF-2α/C-MYC signals. | 26973243 | |||||