LncRNA Information
ID EL0870 Name Miat Aliases 3632434I06; A230057G18Rik; Rncr2; gomafu
Species Mus musculus Chromosome 5 Start site 112213228
End site 112229395 Chain minus Exon NO. 7
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_003718, NR_033657
Ensembl ENSMUSG00000097767 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
neuropsychiatric disorders RNA-seq, qRT-PCR, knockdown, ChIP, RIP prefrontal cortex of adult mice down-regulated expression lncRNAs plays an important role in the epigenetic regulation of adaptive behavior, and the perturbation of Gomafu may be related to anxiety and the development of neuropsychiatric disorders 25792222
 


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
combined full-length mESC transcriptome genomic mapping data with chromatin immunoprecipitation genomic location maps of the key mESC transcription factors mouse embryonic stem cells (mESCs) N/A Interaction potential roles in pluripotency 20026622
IRES-GFP fusion approach mouse retinal cell up-regulated regulation regulating mammalian retinal cell fate specification 20459797
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
Oct4 DNA-TF regulation AK028326 is activated by the transcription factor OCT4. 20026622 LncRNADisease
Oct4 and Nanog RNA-DNA binding AK028326 (Oct4-activated) and AK141205 (Nanog-repressed), are direct targets of Oct4 and Nanog 20026622
BMI1 RNA-Protein regulation Our results revealed that Gomafu plays a role in mediating anxiety-like behavior and suggest that this may occur through an interaction with a key member of the polycomb repressive complex 1, BMI1, which regulates the expression of the schizophrenia-related gene beta crystallin(Crybb1). 25792222