LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL0860 | Name | Mdrl | Aliases | 2310010G23Rik | |
Species | Mus musculus | Chromosome | X | Start site | 36814771 | |
End site | 36817185 | Chain | minus | Exon NO. | 2 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_131979 | |
Ensembl | ENSMUSG00000097468 | Sequence |
Function (not disease relevant) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
knockdown | N/A | N/A | interaction | MDRL affects the processing of miR-484 primary transcript in nucleus and regulates the mitochondrial network by targeting miR-361 and miR-484. MDRL inhibits mitochondrial fission and apoptosis by downregulating miR-361, which in turn relieves inhibition of miR-484 processing by miR-361. | 25057983 | ||||
Interaction | |||||||||
---|---|---|---|---|---|---|---|---|---|
Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
miR-361 | RNA-RNA | binding | MDRL could directly bind to miR-361 and downregulate its expression levels, which promotes the processing of pri-miR-484. | 25057983 | |||||