LncRNA Information | ||||||
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ID | EL0775 | Name | lncLGR | Aliases | N/A | |
Species | Mus musculus | Chromosome | N/A | Start site | N/A | |
End site | N/A | Chain | N/A | Exon NO. | N/A | |
Assembly | N/A | Class | N/A | NCBI accession | AK028540 | |
Ensembl | N/A | Sequence |
Function (not disease relevant) | |||||||||
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Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
lncLGR knockdown enhances GCK expression | fasted mice | up-regulated | N/A | lncLGR knockdown enhances GCK expression and glycogen storage lncLGR knockdown enhances GCK expression and glycogen storage | 26904944 | ||||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
GCK | RNA-DNA | regulation | lncLGR facilitates the recruitment of hnRNPL to the GCK promoter and suppresses GCK transcription. | 26904944 | |||||
heterogenous nuclear ribonucleoprotein L (hnRNPL) | RNA-DNA | binding | lncLGR specifically binds to heterogenous nuclear ribonucleoprotein L (hnRNPL), which is further confirmed to be a transcriptional repressor of GCK in vivo. | 26904944 | |||||