LncRNA Information
ID EL0663 Name LINC00635 Aliases LINC00635-001
Species Homo sapiens Chromosome 3 Start site 107840228
End site 107882000 Chain minus Exon NO. 12
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_024276, NR_015414
Ensembl ENSG00000241469 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
non-small cell lung cancer microarray, qRT-PCR gefitinib-sensitive HCC827 cells and gefitinib-resistant HCC827-8-1 cells up-regulated interaction Silencing of LINC00635-001 alone did not remarkably impact HCC827-8-1 cells, but its combination with gefitinib treatment inhibited Akt activation and sensitized HCC827-8-1 cells to gefitinib-induced cytotoxicity. 26792719
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
Akt RNA-Protein regulation Silencing of LINC00635-001 alone did not remarkably impact HCC827-8-1 cells, but its combination with gefitinib treatment inhibited Akt activation and sensitized HCC827-8-1 cells to gefitinib-induced cytotoxicity. 26792719