LncRNA Information
ID EL0630 Name Khps1 Aliases N/A
Species Homo sapiens Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class antisense NCBI accession N/A
Ensembl N/A Sequence N/A


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
N/A N/A N/A interaction Khps1 activates SPHK1 expression by recruiting the histone acetyltransferase p300/CBP to the SPHK1 promoter, which leads to local changes of the chromatin structure that ensures E2F1 binding and enhances transcription. 26590717
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
SPHK1 RNA-DNA binding Mechanistically, this is achieved by direct association of Khps1 with a homopurine stretch upstream of the transcription start site of SPHK1, which forms a DNA-RNA triplex that anchors the lncRNA and associated effector proteins to the gene promoter. 26590717