LncRNA Information
ID EL0607 Name IFNG-AS1 Aliases GS1-410F4.2; NEST; Tmevpg1
Species Homo sapiens Chromosome 12 Start site 67989445
End site 68234686 Chain plus Exon NO. 5
Assembly Ensembl Release 89 Class antisense NCBI accession NR_104124, NR_104125
Ensembl ENSG00000255733 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
Sjögren syndrome N/A CD4(+) T cells of 25 Sjögren syndrome (SS) patients and 25 healthy donors up-regulated expression The level of expression of TMEVPG1 was correlated with the level of SSA, ESR and IgG. 26440590
Hashimoto's Thyroiditis N/A Twenty-eight HT patients and 20 healthy controls up-regulated interaction Enhanced expression of lncRNA-IFNG-AS1 contributes to Th1 cell response in HT patients and may be involved in the pathogenesis of HT. 26634912
multiple sclerosis N/A N/A N/A N/A Tmevpg1 (IFNG-AS1) is another lncRNA that may be involved in MS. 12719555 LncRNADisease
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
IgG RNA-Protein regulation The level of expression of TMEVPG1 was correlated with the level of SSA, ESR and IgG. 26440590
IFNG RNA-Protein regulation IFNG-AS1 regulated the expression of IFNG at both transcriptional and translational level in human CD4(+) T cells. Strong positive correlations between the increased transcript level of IFNG-AS1 and the increased transcript level of T-bet or IFNG were revealed in thyroid tissues from HT patients. 26634912