LncRNA Information
ID EL0562 Name HAR1B Aliases HAR1R; LINC00065; NCRNA00065
Species Homo sapiens Chromosome 20 Start site 63095493
End site 63102319 Chain minus Exon NO. 2
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_003245
Ensembl ENSG00000231133 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
Huntington's disease N/A N/A N/A expression HAR1, a deeply conserved genomic region consisting of a cis-antisense pair of structured lncRNAs (HAR1F and HAR1R) (2, 23) located ~80 kb from the neural microRNA, miR-124-3. HAR1 levels are significantly lower in the striatum of HD patients. 20179156 LncRNADisease
Alzheimer's disease N/A N/A N/A N/A Schizophrenia spectrum disorders and AD have also been linked with the rheelin (RELN) gene and its antisense transcript HAR1 22817756 LncRNADisease
schizophrenia N/A N/A N/A N/A Schizophrenia spectrum disorders and AD have also been linked with the rheelin (RELN) gene and its antisense transcript HAR1 22817756 LncRNADisease
Huntington's disease N/A N/A N/A regulation HAR1 has also been implicated in HD, where the transcriptional repressor RE-1-silencing transcription factor (REST) enters pathologically into the nucleus, leading to the repression of several important neuronal genes. 23562612 LncRNADisease