LncRNA Information
ID EL0512 Name FRLnc1 Aliases N/A
Species Homo sapiens Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
gastric cancer microarray, qPCR, knockdown etc. gastric cancer tissue, cell lines (MGC803, AGS, BGC823, and SGC7901) up-regulated interaction The RNA level of FRLnc1 is upregulated in 49 % (20/41) of cancer samples compared with neighboring non-cancerous stomach tissues. We also identified TGFb1 and Twist as the downstream effectors of FRLnc1 in the regulation of cell migration. Our findings suggest that FRLnc1 is involved in gastric cancer cell migration and for the first time set up the link between FOXM1 and LncRNA in cancer. 25907137 Lnc2Cancer
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
FOXM1 RNA-DNA co-expression FRLnc1 expression is positively correlated with FOXM1 level. 25907137