LncRNA Information
ID EL0293 Name ceruloplasmin Aliases NRCP
Species Mus musculus Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
ovarian cancer knockdown orthotopic mouse model of ovarian cancer up-regulated interaction NRCP was highly upregulated in ovarian tumors, and knockdown of NRCP resulted in significantly increased apoptosis, decreased cell proliferation, and decreased glycolysis compared with control cancer cells. In an orthotopic mouse model of ovarian cancer, siNRCP delivered via a liposomal carrier significantly reduced tumor growth compared with control treatment. 26686630
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
STAT1 and RNA polymerase II RNA-Protein binding We identified NRCP as an intermediate binding partner between STAT1 and RNA polymerase II, leading to increased expression of downstream target genes such as glucose-6-phosphate isomerase. 26686630