LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL0271 | Name | CASC15 | Aliases | LINC00340 | |
Species | Homo sapiens | Chromosome | 6 | Start site | 21664772 | |
End site | 22368328 | Chain | plus | Exon NO. | 12 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_015410 | |
Ensembl | ENSG00000272168 | Sequence |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
neuroblastoma | RNA-seq, qPCR, knockdown, Luciferase reporter assay, RNA-FISH etc. | Neuroblastoma cell lines | down-regulated | mutation | Here we report that the most highly significant single-nucleotide polymorphism (SNP) associations reside within CASC15, a long noncoding RNA that we define as a tumor suppressor at 6p22. Low-level expression of a short CASC15 isoform (CASC15-S) associated highly with advanced neuroblastoma and poor patient survival. | 26100672 | Lnc2Cancer | ||