LncRNA Information
ID EL0251 Name BX647187 Aliases N/A
Species Homo sapiens Chromosome 3 Start site 111096428
End site 111098930 Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
prostate cancer qPCR, Western bolt, Northern bolt, knockdown etc. prostate cancer tissue, cell lines (LNCaP, PC3, Du145) differential expression interaction Our results showed that Hec1 mRNA and protein were significantly overexpressed in Human PCa tissues and several PCa cell lines. Silencing Hec1 markedly suppressed proliferation, promoted apoptosis and induced cell-cycle arrest in G2/M-phase in PCa cells. Through bioinformatics analysis and knockdown Hec1 in PCa cells, we found LncRNA BX647187 was positively regulated by Hec1. We further demonstrated that suppression of BX647187 in PCa cells significantly reduced cell proliferation and promoted apoptosis. 26612002 Lnc2Cancer
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
Hec1 RNA-Protein regulation LncRNA BX647187 was positively regulated by Hec1. 26612002