LncRNA Information
ID	EL0011	Name	9530018H14Rik	Aliases	lncRNA-HIT
Species	Mus musculus	Chromosome	6	Start site	N/A
End site	N/A	Chain	N/A	Exon NO.	N/A
Assembly	N/A	Class	N/A	NCBI accession	AK020562
Ensembl	N/A	Sequence

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
breast cancer	qPCR, Luciferase reporter assay etc.	breast cancer tissue, cell lines(NMuMG, 4T1)	up-regulated	expression	The level of expression of lncRNA-HIT in normal breast tissue was low and gradually increased to invasive carcinoma suggesting lncRNA-HIT may play a role in tumor progression in humans. These data further support the findings demonstrating the involvement of lncRNA-HIT in EMT and invasion as observed in NMuMG and 4T1 cells, and suggest that conserved human lncRNA-HIT could play a pivotal role in breast cancer metastasis.	25605728	Lnc2Cancer

Function (not disease relevant)
Methods	Sample/condition	Expression pattern	Dysfunction type	Description	PMID	Source
ChIRP-seq, siRNA-mediated reductions	E 11 mouse embryos	up-regulated	interaction	Mechanistically the LncRNA-HIT siRNA treatments impacted pro-chondrogenic gene expression by reducing H3K27ac or p100 activity, confirming that LncRNA-HIT is essential for chondrogenic differentiation in the limb mesenchyme.	26633036

Interaction
Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
p100 and CBP	RNA-Protein	binding	In the limb mesenchyme, LncRNA-HIT was found to be retained in the nucleus, forming a complex with p100 and CBP.	26633036