LncRNA Information
ID	EL0883	Name	MIR99AHG	Aliases	C21orf34; C21orf35; LINC00478; MONC
Species	Homo sapiens	Chromosome	21	Start site	15928296
End site	16627397	Chain	plus	Exon NO.	18
Assembly	Ensembl Release 89	Class	lincRNA	NCBI accession	NR_136541, NR_136542, NR_027790, NR_111005, NR_111004, NR_136552, NR_136551, NR_027791, NR_136543, N
Ensembl	ENSG00000215386	Sequence

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
acute megakaryoblastic leukemia	qPCR etc.	blood, cell lines (CMK, Meg-01, K562, HT1080 and 293 T etc.)	up-regulated	N/A	Here we report that lncRNAs MONC and MIR100HG are highly expressed in AMKL blasts. The transcripts were mainly localized in the nucleus and their expression correlated with the corresponding miRNA clusters. Knockdown of MONC or MIR100HG impeded leukemic growth of AMKL cell lines and primary patient samples. Our study reveals an unprecedented function of lncRNAs MONC and MIR100HG as regulators of hematopoiesis and oncogenes in the development of myeloid leukemia.	25027842	Lnc2Cancer