| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0688 | Name | LINC01207 | Aliases | N/A | |
| Species | Homo sapiens | Chromosome | 4 | Start site | 164754064 | |
| End site | 164803795 | Chain | plus | Exon NO. | 3 | |
| Assembly | Ensembl Release 89 | Class | N/A | NCBI accession | NR_038834 | |
| Ensembl | ENSG00000248771 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| lung adenocarcinoma | qPCR, Western blot, knockdown, RIP, ChIP etc. | NSCLC tissues and adjacent non-tumor tissues, cell lines(A549) | up-regulated | interaction | LINC01207 was significantly up-regulated in LAD tissues compared with paired non-tumor tissues, while there was no significant differences between LSCC tissues and adjacent non-tumor tissues. The expression level of LINC01207 was associated with TNM stage of LAD patients, and higher LINC01207 level indicated advanced TNM stage and shorter survival. | 26693067 | Lnc2Cancer | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| Bad | RNA-DNA | regulation | LINC01207 could bind with EZH2 and mediated trimethylation of histone 3 lysine 27 at the promoter region of Bad, an important pro-apoptotic gene. | 26693067 | |||||
| EZH2 | RNA-Protein | binding | LINC01207 could bind with EZH2 and mediated trimethylation of histone 3 lysine 27 at the promoter region of Bad, an important pro-apoptotic gene. | 26693067 | |||||