LncRNA Information
ID EL0682 Name LINC01024 Aliases MA-linc1
Species Homo sapiens Chromosome 5 Start site 140072857
End site 140108630 Chain minus Exon NO. 4
Assembly Ensembl Release 89 Class antisense NCBI accession NR_102741, NR_102740, NR_102739
Ensembl ENSG00000245146 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
lung cancer qPCR, Western blot, knockdown etc. cell lines (H1299) up-regulated interaction We employed qPCR to analyze MA-linc1 levels in four cell lines: U2OS and H1299 cells, as well as the human embryonic lung fibroblasts, WI38, and another human osteosarcoma cell line, SAOS-2, each expressing the conditionally active E2F1. This analysis demonstrated that activation of the ectopic E2F1 resulted in a significant increase in MA-linc1 RNA levels in all four cell lines. 26337085 Lnc2Cancer
osteosarcoma qPCR, Western blot, knockdown etc. cell lines (U2OS, SAOS-2) up-regulated expression We employed qPCR to analyze MA-linc1 levels in four cell lines: U2OS and H1299 cells, as well as the human embryonic lung fibroblasts, WI38, and another human osteosarcoma cell line, SAOS-2, each expressing the conditionally active E2F1. This analysis demonstrated that activation of the ectopic E2F1 resulted in a significant increase in MA-linc1 RNA levels in all four cell lines. 26337085 Lnc2Cancer
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
Purα RNA-DNA regulation MA-linc1 predominantly functions in cis to repress expression of its neighboring gene, Purα, which is often deleted in human cancers and whose ectopic expression inhibits cell cycle progression. 26337085