LncRNA Information
ID EL0570 Name HIF1A-AS2 Aliases 3'aHIF-1A; aHIF
Species Homo sapiens Chromosome 14 Start site 61715558
End site 61751097 Chain minus Exon NO. 1
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_045406
Ensembl ENSG00000258667 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
osteosarcoma microarray, qPCR etc. primary osteosarcoma tissue up-regulated N/A The results demonstrated that ASLNC21868, ASLNC22124, ASLNC23844, ASLNC24587, BE503655 and BC050642 were over-regulated and that ASLNC00339, ASLNC11435, ASLNC13387 and ASLNC18814 were under-regulated in the osteosarcoma samples compared with normal samples. The qPCR results and microarray data are consistent. 23466354 Lnc2Cancer
kidney cancer N/A N/A N/A expression Diagnostic and discriminative marker 24373479 LncRNADisease
acute myocardial infarction N/A N/A N/A N/A Level of hypoxia inducible factor 1A antisense RNA 2 was higher in patients with MI than in healthy volunteers (P<0.01) 25035150 LncRNADisease
gastric cancer qPCR etc. cancerous gastric tissue, blood (serum) up-regulated expression The expression of HIF1A-AS2 was upregulated in GC tumorous tissues compared with the adjacent normal tissues (P < 0.001). Its overexpression was correlated with TNM stages (P = 0.008), tumor invasion (P = 0.016), lymph node metastasis (P = 0.042), and poor prognosis (P = 0.001). 25686741 Lnc2Cancer
renal cancer qPCR etc. renal cancer tissue up-regulated expression overexpressed in human renal cancer and during hypoxia. 9923855 LncRNADisease Lnc2Cancer
bladder cancer SV-HUC-1 cells bladder cancer tissue and cells up-regulated N/A Overexpression of HIF1A-AS2 in SV-HUC-1 cells could promote cell proliferation cell migration and anti-apoptosis 27018306