| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0488 | Name | FAM3D-AS1 | Aliases | lnc-KCTD6-3 | |
| Species | Homo sapiens | Chromosome | 3 | Start site | 58607080 | |
| End site | 58634440 | Chain | plus | Exon NO. | 4 | |
| Assembly | Ensembl Release 89 | Class | antisense | NCBI accession | NR_134853 | |
| Ensembl | ENSG00000244383 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| tongue cancer | RNA-seq, qPCR etc. | cell lines (UMSCC-10B, HN-12) | down-regulated | N/A | We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration. | 25904139 | LncRNADisease Lnc2Cancer | ||
| pharyngeal cancer | RNA-seq, qPCR etc. | cell lines (HN-1, HN-30) | down-regulated | N/A | Overexpression of lnc-KCTD6-3 reduced the expression of NANOG | 25904139 | LncRNADisease Lnc2Cancer | ||
| laryngeal cancer | RNA-seq, qPCR etc. | cell lines (UMSCC-22B) | down-regulated | N/A | Ectopic expression of lnc-LCE5A-1 increased the expression of CDH-1 in HNSCC cells, while decreasing the expression of OCT-4, NANOG, and VIM. | 25904139 | LncRNADisease Lnc2Cancer | ||