LncRNA Information
ID EL0347 Name Dlx1as Aliases Dix1as; Dlx1os
Species Mus musculus Chromosome 2 Start site 71516454
End site 71537891 Chain minus Exon NO. 2
Assembly Ensembl Release 89 Class antisense NCBI accession NR_002854
Ensembl ENSMUSG00000084946 Sequence


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
Biochemical analysis midgestation mouse brain N/A expression Antisense dlx-1 and -6 have their highest expression in the svz. 9415433
compared between freshly-isolated and cultured dental mesenchymal cells mouse dental mesenchymal cells down-regulated in dental mesenchymal cells; up-regulated in odontogenic dental mesenchymal tissue N/A loss of odontogenic potential 26986487
RNA-seq, RNA CaptureSeq, and ChIP-seq adult mouse subventricular zone neural stem cell lineage N/A expression shRNA-mediated knockdown of two such lncRNAs, Six3os and Dlx1as, indicate roles for lncRNAs in the glial-neuronal lineage specification of multipotent adult stem cells. 23583100
RT-PCR N/A N/A interaction Mice devoid of Dlx1as RNA are viable and fertile, and display a mild skeletal and neurological phenotype reminiscent of a Dlx1 gain-of function phenotype, suggesting a role for this non-coding antisense RNA in modulating Dlx1 transcript levels and stability. 23415800
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
Dlx RNA-RNA co-expression Evf2, Dlx1as, and Dlx4as exhibit similar expression profiles to the associated Dlx genes. 18562676 LncRNADisease
Dlx1 RNA-RNA regulation The reciprocal relationship between Dlx1as and Dlx1 places this sense-antisense pair into a growing class of mammalian lncRNA-mRNA pairs characterized by inverse regulation. 23415800