LncRNA Information
ID	EL1216	Name	Smad7	Aliases	Madh7
Species	Mus musculus	Chromosome	18	Start site	75367529
End site	75395935	Chain	plus	Exon NO.	4
Assembly	Ensembl Release 89	Class	processed transcript	NCBI accession	N/A
Ensembl	ENSMUSG00000025880	Sequence	N/A

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
breast cancer	RNA sequencing, small interfering RNA	mouse mammary gland epithelial cell lines and breast cancer cell lines	N/A	interaction	lncRNA-Smad7 has anti-apoptotic functions, as a target of TGF-β.	24863656

Interaction
Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
TGF-β	RNA-Protein	regulation	Suppression of lncRNA-Smad7 expression cancelled the anti-apoptotic function of TGF-β. In contrast, forced expression of lncRNA-Smad7 rescued apoptosis induced by a TGF-β type I receptor kinase inhibitor in the mouse breast cancer cell line JygMC(A).	24863656