| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1063 | Name | PEG10 | Aliases | EDR; HB-1; MEF3L; Mar2; Mart2; RGAG3 | |
| Species | Homo sapiens | Chromosome | 7 | Start site | 94656325 | |
| End site | 94669695 | Chain | plus | Exon NO. | 2 | |
| Assembly | Ensembl Release 89 | Class | processed transcript | NCBI accession | N/A | |
| Ensembl | ENSG00000242265 | Sequence | N/A | |||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| diffuse large B-cell lymphoma | qPCR, knockdown etc. | DLBCL tissue, cell lines (OCI-LY-3, OCI-LY-7, OCI-LY-10 etc.) | up-regulated | expression | We first found that the expression of PEG10 was upregulated in DLBCL tumorous tissues and that cell lines compared with the normal. Moreover, we illustrated that PEG10 was significantly correlated with B symptoms, IPI score, CHOP-like treatment and rituximab. | 25864113 | Lnc2Cancer | ||
| esophageal cancer | qPCR, Western blot etc. | esophageal cancer tissue, cell lines (EC9706, KYSE150) | up-regulated | expression | LncRNA PEG10 was expressed at higher levels in esophageal cancer tissues than in adjacent non-neoplastic tissues (P<0.05). This relatively high expression was significantly associated with the occurrence of lymph node metastases (P<0.05). Apoptosis and migration rates were significantly decreased in two esophageal cancer cell lines (EC9706 and KYSE150) transfetced with si-LncRNA PEG10 (P<0.05). | 25591808 | Lnc2Cancer | ||