LncRNA Information
ID EL1048 Name Paupar Aliases N/A
Species Mus musculus Chromosome 2 Start site 105657862
End site 105660692 Chain minus Exon NO. 1
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_117095
Ensembl ENSMUSG00000102424 Sequence


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
knockdown N2A mouse neuroblastoma cells N/A N/A Knockdown of Paupar disrupts the normal cell cycle profile of neuroblastoma cells and induces neural differentiation. Paupar acts in a transcript-dependent manner both locally, to regulate Pax6, as well as distally by binding and regulating genes on multiple chromosomes, in part through physical association with PAX6 protein. Paupar binding sites are enriched near promoters and can function as transcriptional regulatory elements whose activity is Modulated by Paupar transcript levels. 24488179
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
PAX6 RNA-Protein binding Paupar acts in a transcript-dependent manner both locally, to regulate Pax6, as well as distally by binding and regulating genes on multiple chromosomes, in part through physical association with PAX6 protein. Paupar binding sites are enriched near promoters and can function as transcriptional regulatory elements whose activity is Modulated by Paupar transcript levels. 24488179