INTERACTION
ID	lncRNA Name	Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
EL1112	RepA	PRC2	RNA-Protein	binding	We discovered a 1.6-kilobase ncRNA (RepA) within Xist and identified the Polycomb complex, PRC2, as its direct target.	18974356	LncRNADisease
EL1112	RepA	Ezh2	RNA-Protein	regulation	Recently, it was shown that a segment of the Xist RNA (called RepA) is important for the targeting of Ezh2 (a component of PRC2) and hence H3K27me3 to the X chromosome.	19239885	LncRNADisease
EL1112	RepA	PRC2	RNA-Protein	binding	RepA is sufficient to recruit PRC2 to chromatin in vivo.	19571179	LncRNADisease
EL1112	RepA	PRC2	RNA-Protein	binding	Tsix represses Xist induction by several means, including altering the chromatin state of Xist, deploying Dnmt3a’s DNA methyltransferase activity, recruiting the RNAi machinery, and interfering with the ability of Xist and RepA RNA to engage Polycomb proteins.	21029862	LncRNADisease
EL1112	RepA	XIST	RNA-DNA	regulation	Recruits PRC2 to the inactive X chromosome in mammals. Necessary for initiation of Xist upregulation and X chromosome silencing.	21256239	LncRNADisease
EL1112	RepA	PRC2	RNA-Protein	binding	Recruits PRC2 to the inactive X chromosome in mammals. Necessary for initiation of Xist upregulation and X chromosome silencing.	21256239	LncRNADisease