INTERACTION
ID	lncRNA Name	Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
EL0884	Mira	Hoxa6	RNA-DNA	regulation	Here, we demonstrate that the long, noncoding RNA (lncRNA) Mistral (Mira) activates transcription of the homeotic genes Hoxa6 and Hoxa7 in mouse embryonic stem cells (mESC) by recruiting MLL1 to chromatin.	21925392	LncRNADisease
EL0884	Mira	Hoxa7	RNA-DNA	regulation	Here, we demonstrate that the long, noncoding RNA (lncRNA) Mistral (Mira) activates transcription of the homeotic genes Hoxa6 and Hoxa7 in mouse embryonic stem cells (mESC) by recruiting MLL1 to chromatin.	21925392	LncRNADisease
EL0884	Mira	MLL1	RNA-Protein	binding	Here, we demonstrate that the long, noncoding RNA (lncRNA) Mistral (Mira) activates transcription of the homeotic genes Hoxa6 and Hoxa7 in mouse embryonic stem cells (mESC) by recruiting MLL1 to chromatin.	21925392	LncRNADisease
EL0884	Mira	Hoxa6 and Hoxa7	RNA-DNA	regulation	Mira-mediated recruitment of MLL1 to the Mira gene triggers dynamic changes in chromosome onformation, culminating in activation of Hoxa6 and Hoxa7 transcription. Hoxa6 and Hoxa7 activate the expression of genes involved in germ layer specification during mESC differentiation in a cooperative and redundant fashion. Our results connect the lncRNA Mira with the recruitment of MLL1 to target genes and implicate lncRNAs in epigenetic activation of gene expression during vertebrate cell-fate determination.	21925392