INTERACTION
ID	lncRNA Name	Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
EL0747	LINC-ROR	Nanog	DNA-TF	regulation	lincRNA-RoR, was shown to be directly targeted by the key pluripotency factors Oct4, Sox2, and Nanog through colocalization of the three factors close its promoter region.	21925379	LncRNADisease
EL0747	LINC-ROR	41186	DNA-TF	regulation	lincRNA-RoR, was shown to be directly targeted by the key pluripotency factors Oct4, Sox2, and Nanog through colocalization of the three factors close its promoter region.	21925379	LncRNADisease
EL0747	LINC-ROR	Sox2	DNA-TF	regulation	lincRNA-RoR, was shown to be directly targeted by the key pluripotency factors Oct4, Sox2, and Nanog through colocalization of the three factors close its promoter region.	21925379	LncRNADisease
EL0747	LINC-ROR	p70S6K1 (RPS6KB1), PDK1 and HIF-1α	RNA-Protein	regulation	siRNA to linc-RoR decreased phosphorylation of p70S6K1 (RPS6KB1), PDK1 and HIF-1α protein expression and increased expression of the linc-RoR target microRNA-145 (miR-145).	24463816
EL0747	LINC-ROR	miR-145	RNA-RNA	regulation	siRNA to linc-RoR decreased phosphorylation of p70S6K1 (RPS6KB1), PDK1 and HIF-1α protein expression and increased expression of the linc-RoR target microRNA-145 (miR-145).	24463816
EL0747	LINC-ROR	NRF2	RNA-TF	binding	NRF2 binds to two specific NRF2 response elements flanking the ROR promoter and that these two NRF2 response elements are equally important to suppress ROR transcription. In addition, we identified associated H3K27me3 chromatin modification and EZH2 binding at the ROR promoter that was dependent on NRF2 binding.	25231996
EL0747	LINC-ROR	TESC	RNA-DNA	regulation	lncRNA ROR occupies and activates the TESC promoter by repelling the histone G9A methyltransferase and promoting the release of histone H3K9 methylation.	26169368
EL0747	LINC-ROR	miR-145	RNA-RNA	regulation	ROR may act as a ceRNA, effectively becoming a sink for miR-145, thereby activating the derepression of core transcription factors Nanog.	26636540