INTERACTION
ID lncRNA Name Interaction target Level of interaction Type of interaction Description PMID Source
EL0300 COOLAIR AtNDX DNA-Protein binding AtNDX associates with single-stranded DNA rather than double-stranded DNA non-sequence-specifically in vitro, and localizes to a heterochromatic region in the COOLAIR promoter in vivo. Single-stranded DNA was detected in vivo as part of an RNA-DNA hybrid, or R-loop, that covers the COOLAIR promoter. R-loop stabilization mediated by AtNDX inhibits COOLAIR transcription, which in turn modifies FLC expression. 23641115
EL0300 COOLAIR FLOWERING LOCUS C (FLC) RNA-DNA regulation Alternative polyadenylation of COOLAIR transcripts correlates with different FLC sense expression states. 24799695
EL0300 COOLAIR cyclin-dependent kinase C (CDKC;2) RNA-Protein regulation In the endogenous gene context, however, the reduction of COOLAIR transcription by cdkc;2 disrupts a COOLAIR-mediated repression mechanism that increases FLC expression. This disruption then feeds back to indirectly increase COOLAIR expression. 24799695