| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0300 | COOLAIR | AtNDX | DNA-Protein | binding | AtNDX associates with single-stranded DNA rather than double-stranded DNA non-sequence-specifically in vitro, and localizes to a heterochromatic region in the COOLAIR promoter in vivo. Single-stranded DNA was detected in vivo as part of an RNA-DNA hybrid, or R-loop, that covers the COOLAIR promoter. R-loop stabilization mediated by AtNDX inhibits COOLAIR transcription, which in turn modifies FLC expression. | 23641115 | |||
| EL0300 | COOLAIR | FLOWERING LOCUS C (FLC) | RNA-DNA | regulation | Alternative polyadenylation of COOLAIR transcripts correlates with different FLC sense expression states. | 24799695 | |||
| EL0300 | COOLAIR | cyclin-dependent kinase C (CDKC;2) | RNA-Protein | regulation | In the endogenous gene context, however, the reduction of COOLAIR transcription by cdkc;2 disrupts a COOLAIR-mediated repression mechanism that increases FLC expression. This disruption then feeds back to indirectly increase COOLAIR expression. | 24799695 | |||