| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0224 | BACE1-AS | APP | RNA-Protein | regulation | BACE1-AS is directly implicated in the increased abundance of Aβ 1–42 in Alzheimer’s disease. | 18587408 | LncRNADisease | ||
| EL0224 | BACE1-AS | BACE1 | RNA-RNA | regulation | The BACE1-antisense transcript (BACE1-AS) regulates BACE1 mRNA and subsequently BACE1 protein expression in vitro and in vivo.expression of BACE1-AS increases BACE1 mRNA stability. | 18587408 | LncRNADisease | ||
| EL0224 | BACE1-AS | BACE1 | RNA-RNA | co-expression | We report here that BACE1-antisense prevents miRNA-induced repression of BACE1 mRNA by masking the binding site for miR-485-5p. Indeed, miR-485-5p and BACE1-antisense compete for binding within the same region in the open reading frame of the BACE1 mRNA. | 20507594 | LncRNADisease | ||
| EL0224 | BACE1-AS | miR-485-5p | RNA-RNA | regulation | We report here that BACE1-antisense prevents miRNA-induced repression of BACE1 mRNA by masking the binding site for miR-485-5p. Indeed, miR-485-5p and BACE1-antisense compete for binding within the same region in the open reading frame of the BACE1 mRNA. | 20507594 | LncRNADisease | ||
| EL0224 | BACE1-AS | miR-485-5p | RNA-RNA | binding | masking the binding site for miR-485-5p | 20507594 | |||
| EL0224 | BACE1-AS | BACE1 | RNA-DNA | regulation | When expression of lncRNA BACE1-AS was silenced using siRNA, BACE1 expression was downregulated and the antiproliferative and anti-invasive effects of anisomycin were reduced. | 26783004 | |||