Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0556 H19 osteoarthritis cDNA array and quantitative RT-PCR OA and normal knee cartilage up-regulated interaction LncRNA H19 acts as a metabolic correlate in cartilage and cultured chondrocytes, while the miR-675 may indirectly influence COL2A1 levels. H19 may not only be an attractive marker for cell anabolism but also a potential target to stimulate cartilage recovery 22527881
EL0861 MEG3 osteoarthritis RT-PCR articular cartilage samples from 20 Osteoarthritis (OA) patients down-regulated expression Maternally expressed gene 3 (MEG3) is a maternally expressed lncRNA and may function as a tumor suppressor by inhibiting angiogenesis. The results show that human MEG3 is significantly downregulated in OA patients compared to normal cartilage samples. MEG3 may be involved in OA development through the regulation of angiogenesis。 26090403
EL1443 VIM2P osteoarthritis qPCR,microarray,Western blot, and immunofluorescence analyses OA cartilage and normal cartilage up-regulated interaction LncRNA-CIR contributes to ECM degradation and plays a key role in the pathogenesis of OA. 24757148