Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A mutation Genotypes of rs10757278 linked to increased risk of atherosclerotic diseases are also associated with decreased expression in PBTL of the INK4/ARF locus, near CDKN2B-AS1 locus. 19343170 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A expression 9p21.3 may promote atherosclerosis by regulating expression of ANRIL, which in turn is associated with altered expression of genes controlling cellular proliferation pathways. 19592466 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A mutation/expression Transcripts EU741058 and NR_003529 of antisense noncoding RNA in the INK4 locus (ANRIL) were significantly increased in carriers of the risk haplotype. 20056914 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A Interaction ANRIL abundantly expressed in atherosclerotic lesions. ANRIL DQ485454 which is not genetically determined by the 9p21 genotype was significantly correlated with MTAP expression. 20637465 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A locus A genetic susceptibility locus. 20956613 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A mutation Individuals homozygous for the atherosclerotic risk allele (rs3217992, A>G;rs1063192, C>T) show decreased expression of ANRIL. 21151960 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A expression Gene expression studies have found that expression levels of CDKN2A/CDKN2B/ANRIL are co-regulated and associated with the risk haplotype and atherosclerosis severity. 21550161 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A mutation The risk alleles for atherosclerosis-related phenotypes were consistently associated with a lower expression of ANRIL when evaluating exons 1-2. Common carotid artery stenosis was associated with a significantly lower (P<0.01) expression of ANRIL (exons 1-2). ANRIL knock-down in VSMC caused significant variation in expression of CDKN2A/B (P<0.05) and reduction of cell growth (P<0.05) in vitro. 22178423 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A mutation Genetic variation in lncRNA genes causes disease and influences susceptibility 23791884 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A regulation The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10. 23813974 LncRNADisease
EL0289 CDKN2B-AS1 atherosclerosis N/A N/A N/A mutation Chr9p21 encodes the long non-coding RNA (ncRNA) antisense non-coding RNA in the INK4 locus (ANRIL). ANRIL expression is associated with the Chr9p21 genotype and correlated with atherosclerosis severity 23861667 LncRNADisease
EL0556 H19 atherosclerosis N/A N/A N/A epigenetics The most pronounced differences of atherosclerotic plaques in DNA methylation levels were registered for a site which is located in CpG-island of imprinted gene H19. 21954592 LncRNADisease
EL0600 HULC atherosclerosis N/A liver cancer up-regulated N/A HULC regulated TNF-α-induced apoptosis through regulation of miR-9 expression 26981838
EL1166 RP5-833A20.1 atherosclerosis N/A N/A N/A N/A Using microarray analysis, the authors found that long noncoding RNA RP5-833A20.1 expression was upregulated, whereas nuclear factor IA (NFIA) expression was downregulated in human acute monocytic leukemia macrophage-derived foam cells. Moreover, they showed that long noncoding RNA RP5-833A20.1 maydecreases NFIA expression by inducing hsa-miR-382-5p expression in vitro. 25265644 LncRNADisease
EL1349 TP53COR1 atherosclerosis N/A N/A N/A N/A The expression of lincRNA-p21 was dramatically downregulated in atherosclerotic plaques of ApoE(-/-) mice, an animal model for atherosclerosis. LincRNA-p21 represses cell proliferation and induces apoptosis in vascular smooth muscle cells and mouse mononuclear macrophage cells in vitro 25156994 LncRNADisease